Protein

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Protein Name Lanosterol synthase
#PDB ID 1
Organism Homo sapiens
Uniprot ID/ACC P48449 (ERG7_HUMAN)
Protein Sequence MTEGTCLRRRGGPYKTEPATDLGRWRLNCERGRQTWTYLQDERAGREQTGLEAYALGLDTKNYFKDLPKAHTAFEGALNGMTFYVGLQAEDGHWTGDYGGPLFLLPGLLITCHVARIPLPAGYREEIVRYLRSVQLPDGGWGLHIEDKSTVFGTALNYVSLRILGVGPDDPDLVRARNILHKKGGAVAIPSWGKFWLAVLNVYSWEGLNTLFPEMWLFPDWAPAHPSTLWCHCRQVYLPMSYCYAVRLSAAEDPLVQSLRQELYVEDFASIDWLAQRNNVAPDELYTPHSWLLRVVYALLNLYEHHHSAHLRQRAVQKLYEHIVADDRFTKSISIGPISKTINMLVRWYVDGPASTAFQEHVSRIPDYLWMGLDGMKMQGTNGSQIWDTAFAIQALLEAGGHHRPEFSSCLQKAHEFLRLSQVPDNPPDYQKYYRQMRKGGFSFSTLDCGWIVSDCTAEALKAVLLLQEKCPHVTEHIPRERLCDAVAVLLNMRNPDGGFATYETKRGGHLLELLNPSEVFGDIMIDYTYVECTSAVMQALKYFHKRFPEHRAAEIRETLTQGLEFCRRQQRADGSWEGSWGVCFTYGTWFGLEAFACMGQTYRDGTACAEVSRACDFLLSRQMADGGWGEDFESCEERRYLQSAQSQIHNTCWAMMGLMAVRHPDIEAQERGVRCLLEKQLPNGDWPQENIAGVFNKSCAISYTSYRNIFPIWALGRFSQLYPERALAGHP
Protein Class ISOMERASE
Synonym(s) -
Gene Symbol -
Gene ID -
Pfam ID PF13243, PF13249
Interpro ID IPR032696, IPR032697, IPR018333, IPR002365, IPR008930
Bound Ligands
HET ID Ligand Type PDB ID Binding Affinity Binding Database Structure Complex Card
R71 Small Molecule 1W6J IC50 : 6.5 nM, IC50 : 223.87 nM, IC50 : 7.5 nM, IC50 : 5.7 nM, IC50 : 170.0 nM BindingDB SHOW