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Protein Download |
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| Protein Name | Epidermal growth factor receptor | |||||
|---|---|---|---|---|---|---|
| #PDB ID | 1 | |||||
| Organism | Homo sapiens | |||||
| Uniprot ID/ACC | P00533 (EGFR_HUMAN) | |||||
| Protein Sequence | MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA | |||||
| Protein Class | TRANSFERASE | |||||
| Synonym(s) | - | |||||
| Gene Symbol | EGFR | |||||
| Gene ID | 1956 | |||||
| Pfam ID | PF00757, PF14843, PF07714, PF01030 | |||||
| Interpro ID | IPR006211, IPR006212, IPR032778, IPR009030, IPR011009, IPR000719, IPR017441, IPR000494, IPR036941, IPR001245, IPR008266, IPR020635, IPR016245 |
Bound Ligands |
HET ID | Ligand Type | PDB ID | Binding Affinity | Binding Database | Structure | Complex Card |
| 0WM | Small Molecule | 4G5J | Kd : 0.14 nM, Kd : 0.23 nM, IC50 : 0.97 nM, Kd : 0.11 nM, Kd : 0.61 nM, Kd : 1.1 nM, Kd : 0.25 nM, Kd : 0.19 nM, Kd : 0.1 nM, Kd : 0.2 nM, Kd : 1.0 nM, IC50 : 0.57 nM, IC50 : 3.8 nM, IC50 : 11.0 nM, IC50 : 12.0 nM, IC50 : 0.97 nM, IC50 : 0.19 nM, IC50 : 0.96 nM, IC50 : 0.4 nM, IC50 : 23.0 nM, IC50 : 1.0 nM, IC50 : 0.5 nM, IC50 : 47.0 nM, IC50 : 1.6 nM, IC50 : 10.0 nM, IC50 : 5.0 nM | BindingDB |  |
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