Protein

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Protein Name Acidic mammalian chitinase
#PDB ID 2
Organism Homo sapiens
Uniprot ID/ACC Q9BZP6 (CHIA_HUMAN)
Protein Sequence MTKLILLTGLVLILNLQLGSAYQLTCYFTNWAQYRPGLGRFMPDNIDPCLCTHLIYAFAGRQNNEITTIEWNDVTLYQAFNGLKNKNSQLKTLLAIGGWNFGTAPFTAMVSTPENRQTFITSVIKFLRQYEFDGLDFDWEYPGSRGSPPQDKHLFTVLVQEMREAFEQEAKQINKPRLMVTAAVAAGISNIQSGYEIPQLSQYLDYIHVMTYDLHGSWEGYTGENSPLYKYPTDTGSNAYLNVDYVMNYWKDNGAPAEKLIVGFPTYGHNFILSNPSNTGIGAPTSGAGPAGPYAKESGIWAYYEICTFLKNGATQGWDAPQEVPYAYQGNVWVGYDNIKSFDIKAQWLKHNKFGGAMVWAIDLDDFTGTFCNQGKFPLISTLKKALGLQSASCTAPAQPIEPITAAPSGSGNGSGSSSSGGSSGGSGFCAVRANGLYPVANNRNAFWHCVNGVTYQQNCQAGLVFDTSCDCCNWA
Protein Class HYDROLASE
Synonym(s)
  •   acidic mammalian chitinase
  • lung-specific protein TSA1902
  • AMCASE
  • CHIT2
  • TSA1902
show 4 synonym(s)
Gene Symbol CHIA
Gene ID 27159
Pfam ID PF01607, PF00704
Interpro ID IPR002557, IPR036508, IPR011583, IPR029070, IPR001223, IPR001579, IPR017853
Bound Ligands
HET ID Ligand Type PDB ID Binding Affinity Binding Database Structure Complex Card
RM8 Small Molecule 3RM8 IC50 : 700.0 nM PDBBind SHOW
RM8 Small Molecule 3RM8 IC50 : 700.0 nM BindingDB SHOW
RM8 Small Molecule 3RM8 IC50 : 700.0 nM Binding MOAD SHOW
3RM Small Molecule 3RM4 Kd : 1690.0 nM, Kd : 210.0 nM, IC50 : 5450.0 nM BindingDB SHOW
3RM Small Molecule 3RM4 IC50 : 210.0 nM Binding MOAD SHOW