Protein

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Protein Name Aldo-keto reductase family 1 member C2
#PDB ID 1
Organism Homo sapiens
Uniprot ID/ACC P52895 (AK1C2_HUMAN)
Protein Sequence MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY
Protein Class OXIDOREDUCTASE
Synonym(s)
  •   aldo-keto reductase family 1 member C2
  • 3-alpha-HSD3
  • chlordecone reductase homolog HAKRD
  • dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III
  • pseudo-chlordecone reductase
  • testicular 17,20-desmolase deficiency
  • trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
  • type II dihydrodiol dehydrogenase
  • AKR1C-pseudo
  • BABP
  • DD
  • DD-2
  • DD/BABP
  • DD2
  • DDH2
  • HAKRD
  • HBAB
  • MCDR2
  • SRXY8
  • TDD
show 19 synonym(s)
Gene Symbol AKR1C2
Gene ID 1646
Pfam ID PF00248
Interpro ID IPR018170, IPR020471, IPR023210, IPR036812
Bound Ligands
HET ID Ligand Type PDB ID Binding Affinity Binding Database Structure Complex Card
IBP Small Molecule 4JTR IC50 : 32700.0 nM, IC50 : 33000.0 nM, IC50 : 100000.0 nM, IC50 : 42400.0 nM BindingDB SHOW