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Protein Download |
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| Protein Name | Muscarinic acetylcholine receptor M2 | |||||
|---|---|---|---|---|---|---|
| #PDB ID | 8 | |||||
| Organism | Homo sapiens | |||||
| Uniprot ID/ACC | P08172 (ACM2_HUMAN) | |||||
| Protein Sequence | MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFFSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRIVKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDEITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNIVARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR | |||||
| Protein Class | SIGNALING PROTEIN | |||||
| Synonym(s) |
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| Gene Symbol | CHRM2 | |||||
| Gene ID | 1129 | |||||
| Pfam ID | PF00001 | |||||
| Interpro ID | IPR000276, IPR017452, IPR001065, IPR000995 |
Bound Ligands |
HET ID | Ligand Type | PDB ID | Binding Affinity | Binding Database | Structure | Complex Card |
| IXO | Small Molecule | 4MQS | Ki : 2.5 nM, Ki : 10.0 nM, Ki : 257.0 nM, Ki : 2.2 nM, Ki : 4.9 nM, Ki : 8.7 nM, EC50 : 0.17 nM, EC50 : 0.08 nM, EC50 : 0.28 nM | BindingDB |  |
SHOW |
| IXO | Small Molecule | 4MQT | Ki : 8.7 nM, Ki : 257.0 nM, Ki : 2.5 nM, Ki : 10.0 nM, Ki : 4.9 nM, Ki : 2.2 nM, EC50 : 0.08 nM, EC50 : 0.17 nM, EC50 : 0.28 nM | BindingDB | |
SHOW |
| 3C0 | Small Molecule | 5ZKC | Kd : 6.4 nM | Binding MOAD |  |
SHOW |
| 3C0 | Small Molecule | 5YC8 | Kd : 6.4 nM | Binding MOAD | |
SHOW |
| QNB | Small Molecule | 3UON |
- |
- |
 |
SHOW |
| QNB | Small Molecule | 5ZK3 |
- |
- |
|
SHOW |
| 3C0 | Small Molecule | 5ZK8 |
- |
- |
|
SHOW |
| IXO | Small Molecule | 6OIK |
- |
- |
|
SHOW |