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Protein Download |
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| Protein Name | Acetylcholinesterase | |||||
|---|---|---|---|---|---|---|
| #PDB ID | 15 | |||||
| Organism | Mus musculus | |||||
| Uniprot ID/ACC | P21836 (ACES_MOUSE) | |||||
| Protein Sequence | MRPPWYPLHTPSLAFPLLFLLLSLLGGGARAEGREDPQLLVRVRGGQLRGIRLKAPGGPVSAFLGIPFAEPPVGSRRFMPPEPKRPWSGVLDATTFQNVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPASPTPVLIWIYGGGFYSGAASLDVYDGRFLAQVEGAVLVSMNYRVGTFGFLALPGSREAPGNVGLLDQRLALQWVQENIAAFGGDPMSVTLFGESAGAASVGMHILSLPSRSLFHRAVLQSGTPNGPWATVSAGEARRRATLLARLVGCPPGGAGGNDTELIACLRTRPAQDLVDHEWHVLPQESIFRFSFVPVVDGDFLSDTPEALINTGDFQDLQVLVGVVKDEGSYFLVYGVPGFSKDNESLISRAQFLAGVRIGVPQASDLAAEAVVLHYTDWLHPEDPTHLRDAMSAVVGDHNVVCPVAQLAGRLAAQGARVYAYIFEHRASTLTWPLWMGVPHGYEIEFIFGLPLDPSLNYTTEERIFAQRLMKYWTNFARTGDPNDPRDSKSPQWPPYTTAAQQYVSLNLKPLEVRRGLRAQTCAFWNRFLPKLLSATDTLDEAERQWKAEFHRWSSYMVHWKNQFDHYSKQERCSDL | |||||
| Protein Class | HYDROLASE | |||||
| Synonym(s) | - | |||||
| Gene Symbol | Ache | |||||
| Gene ID | 11423 | |||||
| Pfam ID | PF08674, PF00135 | |||||
| Interpro ID | IPR029058, IPR014788, IPR002018, IPR019826, IPR019819, IPR000997 |
Bound Ligands |
HET ID | Ligand Type | PDB ID | Binding Affinity | Binding Database | Structure | Complex Card |
| 5GZ | Small Molecule | 4BTL | IC50 : 2500.0 nM | PDBBind |  |
SHOW |
| 5GZ | Small Molecule | 4BTL | IC50 : 2500.0 nM | BindingDB | |
SHOW |
| 5GZ | Small Molecule | 4BTL | IC50 : 2500.0 nM | Binding MOAD | |
SHOW |
| A36 | Small Molecule | 4B80 | IC50 : 40000.0 nM | PDBBind |  |
SHOW |
| A36 | Small Molecule | 4B80 | IC50 : 40000.0 nM | BindingDB | |
SHOW |
| A36 | Small Molecule | 4B80 | IC50 : 40000.0 nM | Binding MOAD | |
SHOW |
| ZN4 | Small Molecule | 4B81 | Kd : 11100.0 nM, Kd : 12000.0 nM | BindingDB |  |
SHOW |
| B3Z | Small Molecule | 4B82 | IC50 : 41000.0 nM | PDBBind |  |
SHOW |
| B3Z | Small Molecule | 4B82 | IC50 : 41000.0 nM | BindingDB | |
SHOW |
| B3Z | Small Molecule | 4B82 | IC50 : 41000.0 nM | Binding MOAD | |
SHOW |
| Q4Q | Small Molecule | 4B7Z | IC50 : 49000.0 nM | PDBBind |  |
SHOW |
| Q4Q | Small Molecule | 4B7Z | IC50 : 49000.0 nM | BindingDB | |
SHOW |
| Q4Q | Small Molecule | 4B7Z | IC50 : 49000.0 nM | Binding MOAD | |
SHOW |
| B3V | Small Molecule | 4B83 | IC50 : 7000.0 nM | PDBBind |  |
SHOW |
| B3V | Small Molecule | 4B83 | IC50 : 7000.0 nM | Binding MOAD | |
SHOW |
| Z5K | Small Molecule | 4B84 | Kd : 14800.0 nM, Kd : 22000.0 nM | BindingDB |  |
SHOW |
| B3W | Small Molecule | 4B85 | IC50 : 88000.0 nM | PDBBind |  |
SHOW |
| B3W | Small Molecule | 4B85 | IC50 : 88000.0 nM | BindingDB | |
SHOW |
| B3W | Small Molecule | 4B85 | IC50 : 88000.0 nM | Binding MOAD | |
SHOW |
| SCK | Small Molecule | 2HA6 | Kd : 48000.0 nM | PDBBind |  |
SHOW |
| SCK | Small Molecule | 2HA6 | Ki : 21000.0 nM | BindingDB | |
SHOW |
| DME | Small Molecule | 2XUD | Ki : 460.0 nM, Ki : 3500.0 nM, Ki : 1000.0 nM | BindingDB |  |
SHOW |
| GC8 | Small Molecule | 5FOQ | IC50 : 26.0 nM, IC50 : 30.0 nM | BindingDB |  |
SHOW |
| SOF | Small Molecule | 5FUM | IC50 : 18000.0 nM, IC50 : 31000.0 nM | BindingDB |  |
SHOW |
| N2K | Small Molecule | 6TD2 |
- |
- |
 |
SHOW |
| E5H | Small Molecule | 6FSD |
- |
- |
 |
SHOW |
| E5K | Small Molecule | 6FSE |
- |
- |
 |
SHOW |