PDB Entry (2ldm)

Download

Visualizer: MichelaNGLo

PDB ID: 2ldm Resolution: None Å Exp. Method: SOLUTION NMR
PMID: 22864287 DOI: 10.1038/nsmb.2353
Protein
Protein Name: PHD finger protein 20
Protein Class: TRANSCRIPTION REGULATOR
Uniprot ID/ACC: Q9BVI0 (PHF20_HUMAN) Organism: Homo sapiens
Gene Symbol: PHF20 Gene ID: 51230
Pocket Descriptors
Volume: 301.184 Depth: 9.02441
Hydrophobicity: 0.787879 Drug Score: 0.855591
Pocket Similarity: Calculate
Ligand
Ligand Name:   (2R)-2-amino-3-(2-dimethylaminoethylsulfanyl)propanoic acid
HET ID:   M2L PubChem:   28212126
DrugBank:   - ChEMBL:   CHEMBL1234161
Canonical SMILES:   CN(CCSC[C@@H](C(=O)O)N)C
Standard InChI:   InChI=1S/C7H16N2O2S/c1-9(2)3-4-12-5-6(8)7(10)11/h6H,3-5,8H2,1-2H3,(H,10,11)/t6-/m0/s1
Molecular Formula:   C7H16N2O2S Mol. Weight:   192.27914 Heavy Atoms:   12
Charge:   0 Is Chiral:   True logP:   0.3934
HBD:   2 HBA:   5 TPSA:   91.86
#Bonds:   12 #Rotatable Bonds:   6 Shape Complexity:   0.85714287
Stereocomplexity:   0.14285715 Ligand Type:   p53K370me2
Binding Affinity
-