PDB Entry (2ldm) Download |
||
Visualizer: MichelaNGLo |
||
PDB ID: 2ldm | Resolution: None Å | Exp. Method: SOLUTION NMR |
PMID: 22864287 | DOI: 10.1038/nsmb.2353 | |
Protein |
|
Protein Name: PHD finger protein 20 | |
Protein Class: TRANSCRIPTION REGULATOR | |
Uniprot ID/ACC: Q9BVI0 (PHF20_HUMAN) | Organism: Homo sapiens |
Gene Symbol: PHF20 | Gene ID: 51230 |
Pocket Descriptors | |
Volume: 301.184 | Depth: 9.02441 |
Hydrophobicity: 0.787879 | Drug Score: 0.855591 |
Pocket Similarity: Calculate |
Ligand |
||
Ligand Name: (2R)-2-amino-3-(2-dimethylaminoethylsulfanyl)propanoic acid | ||
HET ID: M2L | PubChem: 28212126 | |
DrugBank: - | ChEMBL: CHEMBL1234161 | |
Canonical SMILES: CN(CCSC[C@@H](C(=O)O)N)C | ||
Standard InChI: InChI=1S/C7H16N2O2S/c1-9(2)3-4-12-5-6(8)7(10)11/h6H,3-5,8H2,1-2H3,(H,10,11)/t6-/m0/s1 | ||
Molecular Formula: C7H16N2O2S | Mol. Weight: 192.27914 | Heavy Atoms: 12 |
Charge: 0 | Is Chiral: True | logP: 0.3934 |
HBD: 2 | HBA: 5 | TPSA: 91.86 |
#Bonds: 12 | #Rotatable Bonds: 6 | Shape Complexity: 0.85714287 |
Stereocomplexity: 0.14285715 | Ligand Type: p53K370me2 |
Binding Affinity |
||
- |