Index Protein Name Organism UniProt ID/ACC #Protein-Ligand Complex(es) 1 14-3-3 protein sigma Homo sapiens (Human) P31947/1433S_HUMAN 11 2 2-aminomuconate 6-semialdehyde dehydrogenase Pseudomonas fluorescens Q83V33/Q83V33_PSEFL 3 3 2-mercaptophenol-alpha3C None None/None 1 4 2'-O-methyltransferase Middle East respiratory syndrome-related coronavirus (MERS-CoV) T2B9U0/T2B9U0_MERS 6 5 3C-like proteinase Porcine epidemic diarrhea virus K4L9I6/K4L9I6_9ALPC 1 6 3C-like proteinase Middle East respiratory syndrome-related coronavirus (MERS-CoV) V9TU12/V9TU12_MERS 1 7 3-oxoacyl-[acyl-carrier-protein] synthase 1 Escherichia coli (strain K12) P0A953/FABB_ECOLI 1 8 3-oxoacyl-[acyl-carrier-protein] synthase 2 Bacillus subtilis (strain 168) O34340/FABF_BACSU 1 9 3-oxoacyl-[acyl-carrier-protein] synthase 3 Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) P9WNG3/FABH_MYCTU 3 10 3-phosphoinositide-dependent protein kinase 1 Homo sapiens (Human) O15530/PDPK1_HUMAN 3 11 4-hydroxyphenylpyruvate 3-dimethylallyltransferase Streptomyces roseochromogenus subsp. oscitans Q8GHB2/CLOQ_STRRC 2 12 A. acutangulus PKS2 Anisodus acutangulus None/None 1 13 ACP_syn_III_C domain-containing protein Photorhabdus laumondii subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01) Q7N4Z6/Q7N4Z6_PHOLL 1 14 Actinidain Actinidia chinensis var. chinensis (Chinese soft-hair kiwi) P00785/ACTN_ACTCC 1 15 Acyl-carrier-protein] S-malonyltransferase Sorangium cellulosum (Polyangium cellulosum) Q4U443/Q4U443_SORCE 1 16 Acyl-CoA:acyl-CoA alkyltransferase Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25) Q8PDX2/OLEA_XANCP 5 17 Agglutinin Marasmius oreades Q8X123/Q8X123_9AGAR 2 18 Aldehyde dehydrogenase, dimeric NADP-preferring Homo sapiens (Human) P30838/AL3A1_HUMAN 2 19 Aldehyde dehydrogenase, mitochondrial Homo sapiens (Human) P05091/ALDH2_HUMAN 1 20 Alpha-aminoadipic semialdehyde dehydrogenase Homo sapiens (Human) P49419/AL7A1_HUMAN 1 21 Amidophosphoribosyltransferase Escherichia coli (strain K12) P0AG16/PUR1_ECOLI 2 22 Ananain Ananas comosus (Pineapple) (Ananas ananas) P80884/ANAN_ANACO 1 23 Arginine deiminase Mycoplasma arginini P23793/ARCA_MYCAR 1 24 Arsenate reductase Staphylococcus aureus P0A006/ARSC_STAAU 1 25 Arsenic methyltransferase Cyanidioschyzon sp. 5508 C0JV69/C0JV69_9RHOD 3 26 Asparagine synthetase [glutamine-hydrolyzing] Homo sapiens (Human) P08243/ASNS_HUMAN 1 27 Aspartate-semialdehyde dehydrogenase Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) A0A0H2UPS5/A0A0H2UPS5_STRPN 1 28 ATP synthase subunit s, mitochondrial Bos taurus (Bovine) P22027/ATP5S_BOVIN 1 29 Aurora kinase A Homo sapiens (Human) O14965/AURKA_HUMAN 1 30 Baculoviral IAP repeat-containing protein 2 Homo sapiens (Human) Q13490/BIRC2_HUMAN 1 31 Bcl-2 homologous antagonist/killer Homo sapiens (Human) Q16611/BAK_HUMAN 1 32 Betaine aldehyde dehydrogenase, chloroplastic Spinacia oleracea (Spinach) P17202/BADH_SPIOL 1 33 Beta-lactamase Bacillus licheniformis P00808/BLAC_BACLI 12 34 Beta-secretase 1 Homo sapiens (Human) P56817/BACE1_HUMAN 3 35 Bifunctional cytochrome P450/NADPH--P450 reductase Bacillus megaterium (strain ATCC 14581 / DSM 32 / JCM 2506 / NBRC 15308 / NCIMB 9376 / NCTC 10342 / NRRL B-14308 / VKM B-512) P14779/CPXB_BACMB 3 36 Botulinum neurotoxin type A Clostridium botulinum (strain Hall / ATCC 3502 / NCTC 13319 / Type A) P0DPI1/BXA1_CLOBH 1 37 Calpain-1 catalytic subunit Homo sapiens (Human) P07384/CAN1_HUMAN 1 38 Calpain-1 catalytic subunit Rattus norvegicus (Rat) P97571/CAN1_RAT 7 39 Camphor 5-monooxygenase Pseudomonas putida (Arthrobacter siderocapsulatus) P00183/CPXA_PSEPU 2 40 Carbonic anhydrase 2 Homo sapiens (Human) P00918/CAH2_HUMAN 4 41 Carbonic anhydrase 5A, mitochondrial Mus musculus (Mouse) P23589/CAH5A_MOUSE 1 42 Caricain Carica papaya (Papaya) P10056/PAPA3_CARPA 1 43 Caspase-1 Homo sapiens (Human) P29466/CASP1_HUMAN 10 44 Caspase-3 Homo sapiens (Human) P42574/CASP3_HUMAN 19 45 Caspase-8 Homo sapiens (Human) Q14790/CASP8_HUMAN 3 46 Cathepsin B Rattus norvegicus (Rat) P00787/CATB_RAT 2 47 Cathepsin B Bos taurus (Bovine) P07688/CATB_BOVIN 11 48 Cathepsin B Homo sapiens (Human) P07858/CATB_HUMAN 3 49 Cathepsin B1 isotype 1 Schistosoma mansoni (Blood fluke) Q8MNY2/Q8MNY2_SCHMA 4 50 Cathepsin B-like cysteine protease Trypanosoma brucei Q6R7Z5/Q6R7Z5_9TRYP 1 51 Cathepsin F Homo sapiens (Human) Q9UBX1/CATF_HUMAN 1 52 Cathepsin K Homo sapiens (Human) P43235/CATK_HUMAN 38 53 Cathepsin K Oryctolagus cuniculus (Rabbit) P43236/CATK_RABIT 1 54 Cathepsin L2 Homo sapiens (Human) O60911/CATL2_HUMAN 1 55 Cathepsin S Mus musculus (Mouse) O70370/CATS_MOUSE 6 56 Cathepsin S Homo sapiens (Human) P25774/CATS_HUMAN 18 57 CDA peptide synthetase I Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) Q9Z4X6/Q9Z4X6_STRCO 2 58 Chloride intracellular channel protein 2 Homo sapiens (Human) O15247/CLIC2_HUMAN 1 59 Choline trimethylamine-lyase Desulfovibrio alaskensis (strain ATCC BAA 1058 / DSM 17464 / G20) (Desulfovibrio desulfuricans (strain G20)) Q30W70/CUTC_DESAG 1 60 Class A sortase SrtA Staphylococcus aureus Q9S446/Q9S446_STAAU 1 61 Clostripain family Parabacteroides merdae ATCC 43184 A7A9N3/A7A9N3_9BACT 1 62 Clostripain-related protein Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482) Q8A866/Q8A866_BACTN 1 63 CmeC Campylobacter jejuni Q8RTE3/Q8RTE3_CAMJU 1 64 Coagulation factor XIII A chain Homo sapiens (Human) P00488/F13A_HUMAN 3 65 Core protein precursor Hepatitis C virus subtype 1b Q99AU2/Q99AU2_9HEPC 1 66 Cruzipain Trypanosoma cruzi P25779/CYSP_TRYCR 17 67 Cyclin-dependent kinase 2 Homo sapiens (Human) P24941/CDK2_HUMAN 8 68 Cysteine protease Trypanosoma brucei rhodesiense Q95PM0/Q95PM0_TRYBR 2 69 Cysteine proteinase Vasconcellea cundinamarcensis (Mountain papaya) (Carica candamarcensis) Q84XA1/Q84XA1_VASCU 1 70 Cysteine proteinase B Leishmania mexicana P36400/LMCPB_LEIME 1 71 Cytoplasmic tyrosine-protein kinase BMX Homo sapiens (Human) P51813/BMX_HUMAN 1 72 Deaminated glutathione amidase Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) P47016/NIT2_YEAST 2 73 Decaprenylphosphoryl-beta-D-ribose oxidase Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) P9WJF0/DPRE1_MYCTO 1 74 Decaprenylphosphoryl-beta-D-ribose oxidase Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) P9WJF1/DPRE1_MYCTU 6 75 Deoxyribose-phosphate aldolase Escherichia coli (strain K12) P0A6L0/DEOC_ECOLI 5 76 Deubiquitinase and deneddylase Dub1 Chlamydia trachomatis serovar L2 (strain 434/Bu / ATCC VR-902B) B0B9A0/CDUB1_CHLT2 2 77 Diacylglycerol acyltransferase/mycolyltransferase Ag85C Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) P9WQN9/A85C_MYCTU 2 78 Diaminopimelate epimerase Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) P44859/DAPF_HAEIN 2 79 Dihydroorotate dehydrogenase (fumarate) Trypanosoma cruzi (strain CL Brener) Q4D3W2/PYRD_TRYCC 2 80 Dihydroorotate dehydrogenase (fumarate) Leishmania major Q4QEW7/Q4QEW7_LEIMA 2 81 Dihydropyrimidine dehydrogenase [NADP(+)] Sus scrofa (Pig) Q28943/DPYD_PIG 1 82 Dionain-1 Dionaea muscipula (Venus flytrap) A0A0E3GLN3/A0A0E3GLN3_DIOMU 1 83 Dipeptidyl peptidase 1 Homo sapiens (Human) P53634/CATC_HUMAN 10 84 Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens (Human) Q02750/MP2K1_HUMAN 1 85 Dual specificity mitogen-activated protein kinase kinase 7 Homo sapiens (Human) O14733/MP2K7_HUMAN 8 86 E3 ubiquitin-protein ligase RNF31 Homo sapiens (Human) Q96EP0/RNF31_HUMAN 6 87 Ephrin type-B receptor 1 Homo sapiens (Human) P54762/EPHB1_HUMAN 1 88 Epidermal growth factor receptor Homo sapiens (Human) P00533/EGFR_HUMAN 15 89 ErfK/YbiS/YcfS/YnhG family protein Enterococcus faecium (strain ATCC BAA-472 / TX0016 / DO) Q3Y185/Q3Y185_ENTFD 1 90 Estrogen receptor Homo sapiens (Human) P03372/ESR1_HUMAN 2 91 Exportin-1 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) P30822/XPO1_YEAST 12 92 Fatty-acid amide hydrolase 1 Rattus norvegicus (Rat) P97612/FAAH1_RAT 10 93 Ferredoxin-dependent glutamate synthase 2 Synechocystis sp. (strain PCC 6803 / Kazusa) P55038/GLTS_SYNY3 1 94 Ferritin light chain Equus caballus (Horse) P02791/FRIL_HORSE 3 95 Fibroblast growth factor receptor 1 Homo sapiens (Human) P11362/FGFR1_HUMAN 5 96 Fibroblast growth factor receptor 4 Homo sapiens (Human) P22455/FGFR4_HUMAN 14 97 Formamidopyrimidine-DNA glycosylase Lactococcus lactis subsp. cremoris (Streptococcus cremoris) P42371/FPG_LACLC 1 98 Fructose-1,6-bisphosphatase 1 Homo sapiens (Human) P09467/F16P1_HUMAN 1 99 Gag-Pol polyprotein Human immunodeficiency virus type 1 group M subtype B (isolate BH10) (HIV-1) P03366/POL_HV1B1 3 100 Genome polyprotein Human enterovirus D68 (EV68) (EV-68) A1E4A3/A1E4A3_HED68 7 101 Genome polyprotein Human enterovirus 71 (EV71) (EV-71) A9XG43/A9XG43_HE71 12 102 Genome polyprotein Coxsackievirus A16 C8CIL7/C8CIL7_9ENTO 1 103 Genome polyprotein Human enterovirus 71 (EV71) (EV-71) E0WWC7/E0WWC7_HE71 1 104 Genome polyprotein Human enterovirus 71 (EV71) (EV-71) E7E815/E7E815_HE71 3 105 Genome polyprotein Echovirus 1 (strain Human/Egypt/Farouk/1951) (E-1) O91734/POLG_EC01F 1 106 Genome polyprotein Hepatitis C virus genotype 1b (strain HC-J4) (HCV) O92972/POLG_HCVJ4 1 107 Genome polyprotein Foot-and-mouth disease virus (isolate Bovine/Germany/O1Kaufbeuren/1966 serotype O) (FMDV) P03305/POLG_FMDVO 1 108 Genome polyprotein Coxsackievirus B3 (strain Nancy) P03313/POLG_CXB3N 1 109 Genome polyprotein Human rhinovirus 2 (HRV-2) P04936/POLG_HRV2 1 110 Genome polyprotein Hepatitis C virus genotype 1b (isolate BK) (HCV) P26663/POLG_HCVBK 4 111 Genome polyprotein Southampton virus (strain GI/Human/United Kingdom/Southampton/1991) (SHV) (Hu/NV/SHV/1991/UK) Q04544/POLG_SOUV3 1 112 Genome polyprotein Enterovirus B Q5DSM6/Q5DSM6_9ENTO 2 113 Genome polyprotein Coxsackievirus B3 Q5UEA2/Q5UEA2_9ENTO 9 114 Genome polyprotein Poliovirus type 1 (strain Mahoney) P03300/POLG_POL1M 1 115 Genome polyprotein Human hepatitis A virus genotype IB (isolate HM175) (HHAV) (Human hepatitis A virus (isolate Human/Australia/HM175/1976)) P08617/POLG_HAVHM 5 116 Genome polyprotein Norwalk virus (strain GI/Human/United States/Norwalk/1968) (Hu/NV/NV/1968/US) Q83883/POLG_NVN68 19 117 Gingipain R2 Porphyromonas gingivalis (strain ATCC BAA-308 / W83) P95493/CPG2_PORGI 1 118 Glutamine-dependent NAD(+) synthetase Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) P9WJJ3/NADE_MYCTU 1 119 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] Escherichia coli (strain K12) P17169/GLMS_ECOLI 1 120 Glutamyl-tRNA reductase Bacteroides fragilis (strain ATCC 25285 / DSM 2151 / JCM 11019 / NCTC 9343) Q5LAQ6/Q5LAQ6_BACFN 1 121 Glutathione reductase, mitochondrial Homo sapiens (Human) P00390/GSHR_HUMAN 1 122 Glutathione S-transferase omega-1 Homo sapiens (Human) P78417/GSTO1_HUMAN 7 123 Glyceraldehyde-3-phosphate dehydrogenase Geobacillus stearothermophilus (Bacillus stearothermophilus) P00362/G3P_GEOSE 1 124 Glyceraldehyde-3-phosphate dehydrogenase A Escherichia coli (strain K12) P0A9B2/G3P1_ECOLI 1 125 Glyceraldehyde-3-phosphate dehydrogenase, glycosomal Trypanosoma cruzi P22513/G3PG_TRYCR 1 126 Glycogen synthase kinase-3 beta Homo sapiens (Human) P49841/GSK3B_HUMAN 1 127 Glyoxalase/bleomycin resistance protein/dioxygenase Thermomonospora curvata (strain ATCC 19995 / DSM 43183 / JCM 3096 / KCTC 9072 / NBRC 15933 / NCIMB 10081 / Henssen B9) D1A230/D1A230_THECD 1 128 Golgi-associated PDZ and coiled-coil motif-containing protein Homo sapiens (Human) Q9HD26/GOPC_HUMAN 1 129 GTPase HRas Homo sapiens (Human) P01112/RASH_HUMAN 9 130 GTPase KRas Homo sapiens (Human) P01116/RASK_HUMAN 43 131 GTPase KRas isoform X2 Erinaceus europaeus (Western European hedgehog) A0A1S2ZE25/A0A1S2ZE25_ERIEU 1 132 Hemoglobin subunit beta Homo sapiens (Human) P68871/HBB_HUMAN 2 133 Histidine--tRNA ligase Trypanosoma cruzi (strain CL Brener) Q4DA54/Q4DA54_TRYCC 1 134 Histone deacetylase-like amidohydrolase Alcaligenes sp. (strain DSM 11172) (Bordetella sp. (strain FB188)) Q70I53/HDAH_ALCSD 1 135 Histone lysine acetyltransferase CREBBP Mus musculus (Mouse) P45481/CBP_MOUSE 1 136 Histone-lysine N-methyltransferase SMYD3 Homo sapiens (Human) Q9H7B4/SMYD3_HUMAN 2 137 Hydroxymethylglutaryl-CoA synthase Enterococcus faecalis (Streptococcus faecalis) Q9FD71/HMGCS_ENTFL 1 138 Immunoglobulin G-binding protein A Staphylococcus aureus P38507/SPA_STAAU 1 139 Inosine-5'-monophosphate dehydrogenase Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii) Q756Z6/Q756Z6_ASHGO 2 140 Inosine-5'-monophosphate dehydrogenase Bacillus anthracis A0A6L8P2U9/A0A6L8P2U9_BACAN 1 141 Inosine-5'-monophosphate dehydrogenase 1 Homo sapiens (Human) P20839/IMDH1_HUMAN 1 142 Interleukin-12 subunit beta Homo sapiens (Human) P29460/IL12B_HUMAN 1 143 Interleukin-2 Homo sapiens (Human) P60568/IL2_HUMAN 3 144 Isocitrate lyase Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) P9WKK7/ACEA_MYCTU 1 145 Isonitrile hydratase InhA Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5) Q4K977/Q4K977_PSEF5 1 146 Isopentenyl-diphosphate Delta-isomerase Escherichia coli (strain K12) Q46822/IDI_ECOLI 1 147 Kelch-like ECH-associated protein 1 Homo sapiens (Human) Q14145/KEAP1_HUMAN 3 148 L,D-transpeptidase 1 Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) O53638/LDT1_MYCTU 1 149 L,D-transpeptidase 2 Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) O53223/LDT2_MYCTO 2 150 L,D-transpeptidase 2 Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) I6Y9J2/LDT2_MYCTU 15 151 LPXTG-site transpeptidase family protein Bacillus anthracis Q81V16/Q81V16_BACAN 1 152 Lys-gingipain W83 Porphyromonas gingivalis Q51817/KGP83_PORGN 3 153 Lysine-specific demethylase 5A Homo sapiens (Human) P29375/KDM5A_HUMAN 3 154 Lysine-specific demethylase 5B Homo sapiens (Human) Q9UGL1/KDM5B_HUMAN 1 155 Lysozyme C Homo sapiens (Human) P61626/LYSC_HUMAN 1 156 Mast/stem cell growth factor receptor Kit Homo sapiens (Human) P10721/KIT_HUMAN 1 157 Methionine aminopeptidase Escherichia coli C3TPN7/C3TPN7_ECOLX 1 158 Methylated-DNA--protein-cysteine methyltransferase Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) Q97VW7/OGT_SACS2 1 159 Methyl-branched alkylpyrone synthesis polyketide synthase-like Pks11 Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) P9WPF3/PKS11_MYCTU 3 160 Mitogen-activated protein kinase 1 Homo sapiens (Human) P28482/MK01_HUMAN 5 161 Mitogen-activated protein kinase 1 Rattus norvegicus (Rat) P63086/MK01_RAT 1 162 Mitogen-activated protein kinase 14 Homo sapiens (Human) Q16539/MK14_HUMAN 2 163 Mitogen-activated protein kinase 3 Homo sapiens (Human) P27361/MK03_HUMAN 1 164 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 Homo sapiens (Human) Q9UDY8/MALT1_HUMAN 1 165 Multidrug efflux outer membrane protein OprN Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) Q9I0Y7/Q9I0Y7_PSEAE 1 166 Multifunctional-autoprocessing repeats-in-toxin Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) Q9KS12/MARTX_VIBCH 1 167 NADP-dependent glyceraldehyde-3-phosphate dehydrogenase Streptococcus mutans serotype c (strain ATCC 700610 / UA159) Q59931/GAPN_STRMU 1 168 NADPH-dependent 7-cyano-7-deazaguanine reductase Bacillus subtilis (strain 168) O31678/QUEF_BACSU 1 169 NADPH-dependent 7-cyano-7-deazaguanine reductase Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) Q9KTK0/QUEF_VIBCH 2 170 N-carbamoylputrescine amidohydrolase, putative Medicago truncatula (Barrel medic) (Medicago tribuloides) G7ITU5/G7ITU5_MEDTR 1 171 NcmC Saccharothrix syringae (Nocardiopsis syringae) A0A1X9WEN9/A0A1X9WEN9_9PSEU 1 172 N(G),N(G)-dimethylarginine dimethylaminohydrolase Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) Q9I4E3/DDAH_PSEAE 1 173 N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 Homo sapiens (Human) O94760/DDAH1_HUMAN 3 174 N-lysine methyltransferase KMT5A Homo sapiens (Human) Q9NQR1/KMT5A_HUMAN 3 175 NmrA family protein Shigella flexneri None/None 1 176 Nuclear receptor subfamily 4 group A member 2 Homo sapiens (Human) P43354/NR4A2_HUMAN 2 177 O-GlcNAcase BT_4395 Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482) Q89ZI2/OGA_BACTN 4 178 Ornithine decarboxylase Trypanosoma brucei brucei P07805/DCOR_TRYBB 1 179 Pantetheinase Homo sapiens (Human) O95497/VNN1_HUMAN 1 180 Papain Carica papaya (Papaya) P00784/PAPA1_CARPA 5 181 Parkinson disease protein 7 Homo sapiens (Human) Q99497/PARK7_HUMAN 6 182 Peptidylarginine deiminase Porphyromonas gingivalis (strain ATCC BAA-308 / W83) Q9RQJ2/PAD_PORGI 1 183 Peroxisome proliferator-activated receptor gamma Homo sapiens (Human) P37231/PPARG_HUMAN 14 184 Phenylpyruvate C(3)-methyltransferase Streptomyces hygroscopicus Q643C8/MPPJ_STRHY 10 185 Phosphate-binding protein PstS Escherichia coli (strain K12) P0AG82/PSTS_ECOLI 1 186 Phosphoenolpyruvate carboxykinase, cytosolic [GTP] Rattus norvegicus (Rat) P07379/PCKGC_RAT 1 187 Phospholipase A and acyltransferase 3 Homo sapiens (Human) P53816/PLAT3_HUMAN 1 188 Phosphomethylpyrimidine kinase Staphylococcus aureus (strain Mu50 / ATCC 700699) A0A0H3JTP0/A0A0H3JTP0_STAAM 1 189 PHOSPHOMETHYLPYRIMIDINE KINASE Staphylococcus aureus None/None 1 190 Phosphonoacetaldehyde dehydrogenase Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti) Q92UV7/PHNY_RHIME 3 191 Photoactive yellow protein Halorhodospira halophila (Ectothiorhodospira halophila) P16113/PYP_HALHA 3 192 Polyprotein P1234 Venezuelan equine encephalitis virus (strain Trinidad donkey) (VEEV) P27282/POLN_EEVVT 1 193 Polyprotein P1234 Getah virus (GETV) Q5Y389/POLN_GETV 1 194 Procathepsin L Homo sapiens (Human) P07711/CATL1_HUMAN 19 195 Proline racemase A Trypanosoma cruzi (strain CL Brener) Q4DA80/PRCMA_TRYCC 2 196 Protease Human adenovirus D serotype 8 (HAdV-8) (Human adenovirus 8) B9A5C1/B9A5C1_ADE08 4 197 Protease Human adenovirus C serotype 2 (HAdV-2) (Human adenovirus 2) P03252/PRO_ADE02 2 198 Proteinaceous RNase P 1, chloroplastic/mitochondrial Arabidopsis thaliana (Mouse-ear cress) Q66GI4/PRRP1_ARATH 4 199 Protein-arginine deiminase type-4 Homo sapiens (Human) Q9UM07/PADI4_HUMAN 2 200 Protein-glutamine gamma-glutamyltransferase 2 Homo sapiens (Human) P21980/TGM2_HUMAN 1 201 Protein S100-B Bos taurus (Bovine) P02638/S100B_BOVIN 2 202 Proto-oncogene tyrosine-protein kinase Src Gallus gallus (Chicken) P00523/SRC_CHICK 11 203 Proto-oncogene tyrosine-protein kinase Src Homo sapiens (Human) P12931/SRC_HUMAN 8 204 Pteridine reductase Trypanosoma brucei brucei O76290/O76290_TRYBB 2 205 Putative amidase Rhizobium leguminosarum bv. viciae (strain 3841) Q1M7F4/Q1M7F4_RHIL3 1 206 Putative betaine aldehyde dehyrogenase Solanum lycopersicum (Tomato) (Lycopersicon esculentum) Q56R04/Q56R04_SOLLC 1 207 Putative conserved lipoprotein LppS Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra) A5U5L6/A5U5L6_MYCTA 1 208 Putative L,D-transpeptidase YkuD Bacillus subtilis (strain 168) O34816/YKUD_BACSU 1 209 Putative periplasmic protein Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168) Q0PB90/Q0PB90_CAMJE 1 210 Queuine tRNA-ribosyltransferase Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4) P28720/TGT_ZYMMO 1 211 RAC-alpha serine/threonine-protein kinase Homo sapiens (Human) P31749/AKT1_HUMAN 3 212 Replicase polyprotein 1a Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (MERS-CoV) (Betacoronavirus England 1) K9N638/R1A_MERS1 8 213 Replicase polyprotein 1a Bat coronavirus HKU4 (BtCoV) (BtCoV/HKU4/2004) P0C6T4/R1A_BCHK4 1 214 Replicase polyprotein 1a Human coronavirus HKU1 (isolate N1) (HCoV-HKU1) P0C6U3/R1A_CVHN1 1 215 Replicase polyprotein 1a Severe acute respiratory syndrome coronavirus (SARS-CoV) P0C6U8/R1A_SARS 10 216 Replicase polyprotein 1a Porcine transmissible gastroenteritis coronavirus (strain Purdue) (TGEV) P0C6V2/R1A_CVPPU 1 217 Replicase polyprotein 1a Avian infectious bronchitis virus (strain M41) (IBV) P0C6V5/R1A_IBVM 1 218 Replicase polyprotein 1a Porcine epidemic diarrhea virus (strain CV777) (PEDV) P0C6V6/R1A_PEDV7 1 219 Replicase polyprotein 1ab Feline coronavirus (strain FIPV WSU-79/1146) (FCoV) Q98VG9/R1AB_FIPV 2 220 Replicase polyprotein 1ab Human coronavirus NL63 (HCoV-NL63) P0C6X5/R1AB_CVHNL 2 221 Replicase polyprotein 1ab Severe acute respiratory syndrome coronavirus (SARS-CoV) P0C6X7/R1AB_SARS 19 222 Replicase polyprotein 1ab Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) (SARS-CoV-2) P0DTD1/R1AB_SARS2 83 223 Retinal dehydrogenase 1 Homo sapiens (Human) P00352/AL1A1_HUMAN 1 224 Retinal dehydrogenase 1 Ovis aries (Sheep) P51977/AL1A1_SHEEP 2 225 Retinal dehydrogenase 2 Homo sapiens (Human) O94788/AL1A2_HUMAN 1 226 Ribosomal protein S6 kinase alpha-3 Mus musculus (Mouse) P18654/KS6A3_MOUSE 1 227 Ribosomal protein S6 kinase alpha-3 Homo sapiens (Human) P51812/KS6A3_HUMAN 2 228 Ricin B-related lectin Polyporus squamosus Q75WT9/Q75WT9_9APHY 1 229 RNA demethylase ALKBH5 Homo sapiens (Human) Q6P6C2/ALKB5_HUMAN 1 230 Serine/threonine-protein kinase Nek2 Homo sapiens (Human) P51955/NEK2_HUMAN 1 231 Soluble cytochrome b562 Escherichia coli P0ABE7/C562_ECOLX 1 232 Sortase A Staphylococcus aureus (strain NCTC 8325 / PS 47) Q2FV99/SRTA_STAA8 1 233 Sortase B Staphylococcus aureus (strain USA300) A0A0H2XI76/A0A0H2XI76_STAA3 1 234 Sortase B Staphylococcus aureus (strain NCTC 8325 / PS 47) Q2FZE3/SRTB_STAA8 2 235 Sortase family protein Staphylococcus aureus CA-347 None/None 1 236 Spermidine synthase, putative Trypanosoma cruzi (strain CL Brener) Q4DA73/Q4DA73_TRYCC 1 237 Spindle pole body-associated protein VIK1 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) Q12045/VIK1_YEAST 1 238 Staphopain A Staphylococcus aureus P81297/SSPP_STAAU 1 239 Streptopain Streptococcus pyogenes None/None 1 240 Streptopain Streptococcus pyogenes P0C0J0/SPEB_STRPY 1 241 Subtilisin Savinase Lederbergia lentus (Bacillus lentus) P29600/SUBS_BACLE 4 242 Succinate-semialdehyde dehydrogenase Synechococcus sp. (strain ATCC 27264 / PCC 7002 / PR-6) (Agmenellum quadruplicatum) B1XMM6/B1XMM6_SYNP2 1 243 Sulfurtransferase Chlorobium limicola (strain DSM 245 / NBRC 103803 / 6330) B3ECE3/B3ECE3_CHLL2 1 244 SUMO-activating enzyme subunit 2 Homo sapiens (Human) Q9UBT2/SAE2_HUMAN 1 245 Superoxide dismutase [Cu-Zn] Homo sapiens (Human) P00441/SODC_HUMAN 4 246 Targeting protein for Xklp2 Homo sapiens (Human) Q9ULW0/AURKA_HUMAN 2 247 T-box transcription factor T Homo sapiens (Human) O15178/TBXT_HUMAN 1 248 TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 Homo sapiens (Human) Q15750/M3K7_HUMAN 6 249 Thiol:disulfide interchange protein DsbA Shigella flexneri P52235/DSBA_SHIFL 1 250 Thioredoxin Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) P9WG67/THIO_MYCTU 1 251 Thymidylate synthase Lactobacillus casei P00469/TYSY_LACCA 1 252 Thymidylate synthase Pneumocystis carinii P13100/TYSY_PNECA 1 253 Thymidylate synthase Trichinella spiralis (Trichina worm) Q9NDD3/Q9NDD3_TRISP 1 254 Thymidylate synthase Homo sapiens (Human) P04818/TYSY_HUMAN 1 255 Thymidylate synthase Mus musculus (Mouse) P07607/TYSY_MOUSE 2 256 Thymidylate synthase Escherichia coli (strain K12) P0A884/TYSY_ECOLI 13 257 Thymidylate synthase Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) (Filobasidiella neoformans) P0CS12/TYSY_CRYNJ 1 258 Thymidylate synthase 1 Bacillus subtilis (strain 168) P0CI79/TYSY1_BACSU 1 259 Toxin B Clostridioides difficile (strain 630) (Peptoclostridium difficile) Q189K3/Q189K3_CLOD6 1 260 Transcriptional regulator, ArsR family Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003) D5AT91/D5AT91_RHOCB 1 261 Transcriptional regulator, PadR-like family Lactococcus lactis subsp. cremoris (strain MG1363) A2RI36/A2RI36_LACLM 1 262 Transforming protein RhoA Homo sapiens (Human) P61586/RHOA_HUMAN 1 263 Tryparedoxin Trypanosoma brucei brucei O77404/TYPX_TRYBB 1 264 Tubulin alpha-1B chain Bos taurus (Bovine) P81947/TBA1B_BOVIN 1 265 Tubulinyl-Tyr carboxypeptidase 1 Homo sapiens (Human) Q7L8A9/VASH1_HUMAN 2 266 Tubulinyl-Tyr carboxypeptidase 2 Homo sapiens (Human) Q86V25/VASH2_HUMAN 1 267 Tumor necrosis factor receptor superfamily member 16 Rattus norvegicus (Rat) P07174/TNR16_RAT 1 268 Tyrosine-protein kinase BTK Homo sapiens (Human) Q06187/BTK_HUMAN 14 269 Tyrosine-protein kinase ITK/TSK Homo sapiens (Human) Q08881/ITK_HUMAN 4 270 Tyrosine-protein kinase JAK3 Homo sapiens (Human) P52333/JAK3_HUMAN 9 271 Tyrosine-protein kinase ZAP-70 Homo sapiens (Human) P43403/ZAP70_HUMAN 1 272 Tyrosine-protein phosphatase non-receptor type 1 Homo sapiens (Human) P18031/PTN1_HUMAN 2 273 Tyrosine-protein phosphatase non-receptor type 13 Homo sapiens (Human) Q12923/PTN13_HUMAN 2 274 Tyrosine-protein phosphatase YopH Yersinia enterocolitica P15273/YOPH_YEREN 2 275 Ubiquitin carboxyl-terminal hydrolase 2 Homo sapiens (Human) O75604/UBP2_HUMAN 1 276 Ubiquitin carboxyl-terminal hydrolase 7 Homo sapiens (Human) Q93009/UBP7_HUMAN 1 277 Ubiquitin-conjugating enzyme E2 N Homo sapiens (Human) P61088/UBE2N_HUMAN 2 278 Ubiquitin thioesterase OTUB2 Homo sapiens (Human) Q96DC9/OTUB2_HUMAN 12 279 UDP-glucose 6-dehydrogenase Homo sapiens (Human) O60701/UGDH_HUMAN 1 280 UDP-N-acetylglucosamine 1-carboxyvinyltransferase Acinetobacter baumannii A0A0R0VXX6/A0A0R0VXX6_ACIBA 1 281 UDP-N-acetylglucosamine 1-carboxyvinyltransferase Aliivibrio fischeri (strain MJ11) (Vibrio fischeri) B5F9P4/MURA_ALIFM 1 282 UDP-N-acetylglucosamine 1-carboxyvinyltransferase Enterobacter cloacae subsp. cloacae (strain ATCC 13047 / DSM 30054 / NBRC 13535 / NCTC 10005 / WDCM 00083 / NCDC 279-56) P33038/MURA_ENTCC 1 283 UDP-N-acetylglucosamine 1-carboxyvinyltransferase Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) P45025/MURA_HAEIN 1 284 UDP-N-acetylglucosamine 1-carboxyvinyltransferase Escherichia coli (strain K12) P0A749/MURA_ECOLI 2 285 UDP-N-acetylglucosamine 1-carboxyvinyltransferase Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) Q9KP62/MURA_VIBCH 1 286 UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) Q97NQ4/MURA1_STRPN 2 287 Uncharacterized protein Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) Q8VK10/Q8VK10_MYCTO 1 288 UPF0678 fatty acid-binding protein-like protein At1g79260 Arabidopsis thaliana (Mouse-ear cress) O64527/Y1926_ARATH 1 289 Urease subunit alpha Sporosarcina pasteurii (Bacillus pasteurii) A0A0H3YL32/A0A0H3YL32_SPOPA 1 290 Urease subunit alpha Sporosarcina pasteurii (Bacillus pasteurii) P41020/URE1_SPOPA 2 291 Ypt/Rab-type GTPase YPT7 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) P32939/YPT7_YEAST 2